Founded in 1997, GTx, Inc. is a biopharmaceutical company dedicated to the development and commercialization of therapeutic products related to men's health. The company's drug discovery and development programs are focused on small molecules that selectively target nuclear hormone receptors for estrogens and androgens. These nuclear hormone receptors are among the best-understood receptor systems, and pharmaceuticals have been developed to either stimulate or block these receptors for over 50 years.

To this end, we are actively recruiting for the following position:

Preclinical, Research Scientist

Role:

The successful candidate will: (1) Design and implement strategies and studies to support
drug development programs, including lead candidate optimization, genetic toxicology,
safety pharmacology, toxicology and toxicokinetics; (2) Oversee data analysis and prepare
technical reports regarding preclinical development studies; (3) Identify and manage
outsourcing partners and studies; and (4) Develop model approaches to evaluate the
toxicological potential of novel therapeutics. In particular, the research scientist will utilize
pertinent research tools to identify, characterize, and optimize lead compounds in support of
GTx, Inc. core business strategies. Research will encompass all aspects of preclinical
development, ranging from in vitro and in vivo proof of principle studies to definitive,
regulated in vivo toxicology and toxicokinetics to transition compounds from Discovery to
Clinical Development at GTx.

Responsibilities:

• Design and implementation of advanced research projects related to the
  development and/or optimization of lead compounds in project area.
• Contribute to other preclinical research projects through technical leadership and
  consultation with professional co-workers, collaborators and staff.
• Responsible for data preparation, analysis, reports, and other documentation for
  management.
• Assist in the preparation of regulatory submissions (IND, NDA, MAA, etc.).
• Attendance and participation in group/departmental meetings.
• Overseeing all aspects of projects to include:
  o Technical conduct of GLP study, as well as interpretation, analysis and
  documentation, and reporting of results.
  o Coordinate studies with management, QA and scientific/technical staff to
  ensure administrative and regulatory compliance.
  o Supervise and direct all scientists and technicians involved in the study.
  o Facilitate communication between test sites to ensure protocols and
  amendments are available (when applicable).
  o Responsible to ensure all raw data are documented and all applicable
  protocols and Standard Operating Procedures are adequately followed by the
  study team.
  o Documentation and corrective action for any deviations in a research study.
  o Signature responsibility to ensure validity of data in project area.

Preferred Qualifications :

• PhD. - pharmacology, toxicology, pathology or related discipline (including DVMor
  MD).
• 2-4 years Post-doctoral or industry experience.
• Adept in multiple scientific disciplines including pharmacology and biochemistry.
• Able to work independently in technical matters.
• Strong, effective communication and organizational skills.
• Ability to work in a team environment.
• Demonstrated evidence of superior writing skills.

Interested candidates should submit resume, list of professional references, and salary requirements to: Human Resources. GTx, Inc. 3 North Dunlap Street, Memphis, TN 38163. Or, CV's can be submitted electronically to: careers@gtxinc.com . Please include the position title in the subject line.